Monograph: |
L-Threonine
Threonine (like Lysine) is deficient in most grains . It requires
the combining of a pulse which contains Threonine
(and Lysine) with a grain, to ensure a complete protein in a
Vegetarian meal.
Deficiency of Threonine results in irritability and generally a
difficult personality. Threonine is very useful in
indigestion and intestinal malfunctions, and prevents excessive
liver fat. Nutrients, are more readily absorbed when
Threonine is present.
The excretion of Threonine which showed the greatest relative
increase, was two to four times higher in pregnancy.
Several antibiotics including Erythromycin are found to affect L-
Threonine absorption, from the intestine thereby
Threonine deficiency can occur.
It is abundant in human plasma, particularly in newborns.
Severe deficiency of Threonine causes neurological
dysfunctions and lameness In experimental animals.
Threonine is an immunostimulant which promotes the growth of
thymus gland. It can also probably promote cell
immune defense functions.
Animal trials confirms that, subjects fed on diets deficient in
Threonine, were more susceptible to infection e.g. by
S.Typhimurium or L-Monocytogenes.
Replenishment of Threonine reversed the susceptibility. The
extrapolation to human models could indicate ways of
minimizing risks for susceptible individuals to specific
infections.
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