Monograph: |
Porcine Insulin
Porcine insulin differs from human insulin
in only one amino acid in the B chain.
The precursor of insulin in the pancreas is proinsulin
which is a single polypeptide chain incorporating
both the A and .B chains of insulin connected by a
peptide termed the C-peptide (or connecting peptide).
Although the insulins of various species may
be similar in composition the proinsulins are not, in
that the sequence and number of amino acids in the
C-peptide may vary considerably.
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