Monograph: |
Triflupromazine Hydrochloride
A white to pale tan crystalline powder with a slight character-
istic odour.
Soluble I in less than I of water and of alcohol and I in 1.7
of chloroform: soluble in acetone: practically insoluble in
ether. Protect from light.
Triflupromazine hydrochloride is a phenothiazine with general
properties similar to those of chlorpromazine. It is
used mainly in the management of psychoses and the
control of nausea and vomiting. Triflupromazine hy-
drochloride is usually given by injection but in some coun-
tries preparations are available for administration by mouth.
In the management of psychosis, the usual dose is 60 to
150 mg daily by intramuscular injection. For the control of
nausea and vomiting 5 io 15 mg is given intramuscularly and
repeated after 4 hours if necessary up to a maximum of 60 mg
daily: a done of I mg to a maximum total daily dose of 3 mg
may be given intravenously.
A suggested intramuscular dose for children over 2 years of
age is 0.2 to 0.25 mg per kg body-weight daily up to a maxi-
mum of 10 mg daily.
Reduced doses should be used in elderly or debilitated pa-
tients.
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