Monograph: |
VIT D2
Ergocalciferol
An antirachitic substance obtained from ergosterol, a sterol
present in fungi and yeasts, by ultraviolet irradiation. White
or almost white, odourless, crystals or white or slightly yel-
low crystalline powder. It is sensitive to air, heat, and light.
Practically insoluble in water; freely soluble or soluble in al-
cohol and in ether: soluble in chloroform and in fatty oils.
Solutions in volatile solvents are unstable and should be used
immediately. Store at a temperature of 2 to 8Β° in hermetically
sealed containers in which the air has been replaced by nitro-
gen. The contents of an opened container should be used im-
mediately. Protect from light.
Stability. A review of the compatibility and stability of com-
ponents of total parenteral solutions when mixed in I-or 3-
litre flexible containers. Vitamin D may bind strongly to
plastic which can lead to significant losses to the bag and ad-
ministration set. Vitamin D losses from paediatric TPN mix-
tures have been estimated to be about 30 to 36% over a 24-
hour administration period. The quantity of vitamin D deliv-
ered depends on infusion rate, type of administration set,
composition of mixture, and total volume infused.
Rest of the properties are similar to vit D, so click to vit D
record for the details.
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