Monograph: |
Dibasic Sodium Phosphate
It specifies for the dihydrate; a white or almost
white powder or colourless crystals; for the dodecahydrate:
colourless, transparent, very efflorescent crystals. The USP
has a monograph for the anhydrous, dihydrate, heptahydrate,
and dodecahydrate forms. It specifies for the dried substance:
awhite powder that readily absorbs moisture; and for the hep-
tahydrate: a colourless or white, granular or caked salt that
effloresces in warm. dry air.
Each g of dibasic sodium phosphate (anhydrous) represents
approximately 14.1 mmol of sodium and 7.0 mmol of phos-
phate. Each g of dibasic sodium phosphate (dihydrate) repre-
sents approximately 11.2 mmol of sodium and 5.6 mmol of
phosphate. Each g of dibasic sodium phosphate (heptahy-
drate) represents approximately 7.5 mmol of sodium and
3.7 mmol of phosphate. Each g of dibasic sodium phosphate
(dodecahydrate) represents approximately 5.6 mmol of sodi-
um and 2.8 mmol of phosphate.
Ph. Eur. solubilities for the dihydrate are soluble in water;
practically insoluble in alcohol: and for the dodecahydrate:
very soluble in water: practically insoluble in alcohol. USP
solubilities are for the dried substance: soluble I in 8 of water:
insoluble in alcohol; and for the heptahydrate: freely soluble
in water; very slightly soluble in alcohol. Store in airtight
containers.
The properties are similar to dibasic pot phosphate ,so click to dibasic pot phosphate for the details.
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