Monograph: |
Diastase
The properties are the same as Amylase , so see below at Amylase record for the details.
Amylase
Indications: Dyspepsia
DESCRIPTION:
CLINICAL PHARMACOLOGY:
Diminution of secretions from exocrine glands is often a result of the normal aging process. Amylase; cellulase; lipase; protease provides a balanced combination of natural proteolytic, amylolytic, cellulolytic and lipolytic enzymes to enhance digestion of proteins, starch and fat in the gastrointestinal tract. These enzymes do not exert any systemic pharmacologic effects. Amylase; cellulase; lipase; protease should be considered an enzyme supplement and not an enzyme replacement therapy. Enzymes in amylase; cellulase; lipase; protease are basically derived from fungal and plant sources and possess a broad spectrum of pH activity. Enzymes are promptly released from the capsules and are bioavailable for digestion of food in the stomach and intestines.
INDICATIONS AND USAGE:
For the relief of functional indigestion when due to enzyme deficiency or imbalance. Amylase; cellulase; lipase; protease relieves symptoms due to faulty digestion including the sensation of fullness after meals, dyspepsia, flatulence, abdominal distention and intolerance to certain foods.
CONTRAINDICATIONS:
Amylase, cellulase, lipase, and protease capsules are contraindicated in patients known to be hypersensitive to pork protein and in patients with acute pancreatitis or with acute exacerbations of chronic pancreatic diseases.
WARNINGS:
Do not administer to patients who are allergic to pork products. Should hypersensitivity occur, discontinue medication and treat symptomatically.
PRECAUTIONS:
Information for the Patient: If capsules are opened, avoid inhalation of the powder. Sensitive individuals may experience allergic reactions.
Carcinogenesis, Mutagenesis, and Impairment of Fertility: Long-term studies in animals have not been performed to evaluate the carcinogenic, mutagenic or impairment of fertility potential of amylase; cellulase; lipase; protease.
Pregnancy Category C: Animal reproduction studies have not been conducted with amylase; cellulase; lipase; protease. It is also not known whether amylase; cellulase; lipase; protease can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Amylase; cellulase; lipase; protease should be given to a pregnant woman only if clearly needed.
Nursing Mothers: It is not known whether amylase; cellulase; lipase; protease is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when amylase; cellulase; lipase; protease is administered to a nursing woman.
ADVERSE REACTIONS:
Virtually unknown. Occasionally a slight looseness of stools may be noticed. If so, dosage should be reduced. Finely powdered pancreatic enzyme may be irritating to the mucous membranes and respiratory tract. Inhalation of the airborne powder may precipitate an asthma attack in sensitive individuals.
OVERDOSAGE:
No systemic toxicity occurs. Excessive dosage may, however, produce a laxative effect.
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